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Nitrofurantoin
Macrobid

  • Furabid / Urolong / Furadantin / Macrodantin
  • ANT022
  • In Stock

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   Manufacturer's Suggested Retail Price (MSRP) per pill is $6.72 ! Buying from us will save you at least 48.96%

Package per pill Price SAVINGS BONUS Order
100mg * 30 pills
$3.43 $102.90 $0.00
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SILVER BONUS
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100mg * 60 pills
$1.99 $119.40 $86.40
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SILVER BONUS
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100mg * 90 pills
$1.53 $137.70 $171.00
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SILVER BONUS
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100mg * 120 pills
$1.29 $154.80 $256.80
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SILVER BONUS
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100mg * 180 pills
$1.06 $190.80 $426.60
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SILVER BONUS
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A bacteriostatic or bactericidal agent depending on the concentration and susceptibility of the infecting organism. Nitrofurantoin is active against some gram positive organisms such as S. aureus, S. epidermidis, S. saprophyticus, Enterococcus faecalis, S. agalactiae, group D streptococci, viridians streptococci and Corynebacterium.

Its spectrum of activity against gram negative organisms includes E. coli, Enterobacter, Neisseria, Salmonella and Shigella. It may be used as an alternative to trimethoprim/sulfamethoxazole for treating urinary tract infections though it may be less effective at eradicating vaginal bacteria.

May also be used in females as prophylaxis against recurrent cystitis related to coitus. Nitrofurantoin is highly stable to the development of bacterial resistance, a property thought to be due to its multiplicity of mechanisms of action.

May be used as an alternative in the treatment of urinary tract infections. May be used by females pericoitally for prophylaxis against recurrent cystitis related to coitus.

Nitrofurantoin exhibits bacteriostatic or bactericidal effects by inhibiting the synthesis of DNA, RNA, protein and cell wall synthesis.

Nitrofurantoin is activated by bacterial flavoproteins (nitrofuran reductase) to active reduced reactive intermediates that are thought to modulate and damage ribosomal proteins or other macromolecules, especially DNA, causing inhibition of DNA, RNA, protein, and cell wall synthesis. The overall effect is inhibition of bacterial growth or cell death.

Metabolism: Partially metabolized in liver to aminofurantoin.

Absorption: Readily absorbed in GI tract primarily in small intestine. Enhanced by food or delayed gastric emptying via enhanced dissolution rate of the drug.

Route of elimination: N/A

Half life: 0.3-1 hour

Affected organisms: Gram negative and gram positive bacteria.

All medicines may cause side effects, but many people have no, or minor, side effects.Some medical conditions may interact with Nitrofurantoin.

Tell your doctor or pharmacist if you have any medical conditions.

Acute toxicity may cause vomiting. Adverse effects include nausea and urine discolouration. Rare hepatotoxic and hypersensitivity reactions have occurred. Hemolytic anemia is a risk in patients with G6PD deficiency. Ascending polyneuropathy may occur with prolonged therapy or in patients with low creatinine clearance.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Carmen
28/Oct/2023

I have found after taking this medicine for several years, without it I go into a UTI. I lose my strength in my legs and ability to walk as well, slow to function as fatigue. With the medication, I don't have a UTI and function as I should. While taking a medication is annoying, it eliminates the UTI and I go on with my day in life.

Kristin
25/Oct/2023

This is by far the best antibiotic I have ever used. It is fast working, best in effectiveness, and has little to now side effects, and also little to no interactions. I recommend it very highly.

Ben
28/Feb/2023

I like this drug. It serves its purpose. I haven't really had any side effects. I take it before intercourse and if i get another infection. I would recommend this drug!

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